Lunes, 20 Mayo 2019 17:21

Viral low tract respiratory infection in the intensive care unit.

Escrito por 

 Congreso Internacional 

González F, Verga F, Albornoz H, Burghi G, Galiana G, Barbato M. Viral low tract respiratory infection in the intensive care unit. XIII World Congresso Intesive Care. – XXII Brazilian Congress of Intensive Care. Brazilian J Int Care 2017;29 (supl 1): s3.

Introduction: Viral severe low respiratory tract infections ar a main cause of admission in the Intensive Care Unit (ICU). Molecular tecniques have increased their identification.

Objective: The aim of this study was to compare features of viral pneumonia with bacterial pneumonia or coinfection.

Methods: Prospective, observational study, included adults patients, with severe community low respiratory tract infections, admitted in ICU between Janury, 2016 – June, 2017. We collected results of real-time reverse-transcriptase-polymerase- chain-reaction (Film Array®).

Results: We included 53 patients, 64,2% mens, aged 60 ±13, Sequential Organ Failure Assessment (SOFA) 10 ±5,5, ICU stay 13 ±13 días, Mechanical Ventilation (MV) was applied in 81%, duration of MV 9,3 ±9 days. ICU mortality 22,6%. We obtained microbiological identification in 36/53 (67%), corresponding 14 viral etiology, 13 bacterial and 9coinfections. Of the 23 viral infections, we identified: 9 Influenza A, 8 Rhinovirus, 3 Sincitial Respiratory Virus, 1 Adenovirus, 1 Coronavirus y 1 Influenza B. Caractheristics of viral exclusively compared to coinfection and bacterial, were: age 54 ±18 vs 60 ±13 (p=0,33); SOFA 10 ±5 vs 10 ±6; ICU stay 19 ±16 vs 14 ±15; sepsis 50% vs 45% (p=0,79); MV 93% vs 77% (p=0,22), respiratory distress syndrome 29% vs 18% (p=0,46), mortality 9% vs 27% (p= 0.19), respectively. Conclusion: Respiratory viruses were the major cause of severe pulmonary infection admitted in the ICU (64%), mainly as an unique agent (39%), presenting similar severity and mortality than bacterial etiology.

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